Tamamo is one of the Four Heavenly Knights.
Tamamo is first seen in the Cave of Treasures in Part 1, but it turns out to be nothing but a fake, a recording essentially from the original timeline to trick Nanabi into guarding the bell. As soon as the ruse is pointed out, it is dispelled and the puppeteer, White Rabbit appears who explains this was so events follow the correct history.
Tamamo is properly met in Yamatai Village at the Kitsune Shrine, just like in the original trilogy. She's extremely sad for an unclear reason, saying cryptically that "it is madness" and that she "grew too attached to this world." Deciding that there's nothing they can do, the hero's team move on.
She's later seen when Alma Elma decides to check on her before assisting Luka in infiltrating Grangold . The succubus tries to convince her to act, but the kitsune keeps telling her that she should stay out of this, as "there's no other way." However, she still decides to step in and save Lazarus and Merlin from a transformed Grangold King. She latter steps in the castle to help Luka's party, who is getting wrecked by her alternate self from the Monster World. She transforms into her true form and face her alter ego while Luka and his party gets attacked by Lilith. Both kitsune ancestors are evenly matched, but Tamamo is limited by the length of her transformation, which is reminded by her opponent. However, Nero and Neris step in and save her, with Nero calling her "master" as they start attacking the other ancestor. She manages to escape when the castle collapse, and is latter seen at the banquet, where she says that she used to be like her but softened a great deal with time. She still refuses to join Luka's party, saying she will instead focus on getting sure that her alternate self remain out of this world.
She's seen in one of the "Upcoming event" sequence, where she examines the Tartarus in Remina that leads to the Monster World, and see a huge rock that likely needed the work of several ancestors to develop. Yao spawns afterwards, and Tamamo guess that this is the result of the upcoming new war between tanukis and kitsunes. As the tanuki queen has been boosted by Black Alice, she tells her first lieutenant that they have to turn to Luka for help.
This version of Tamamo is the only Knight who didn't fight Luka and just rather retire in her home at Yamatai Village until Alma Elma convinces her to not give up on others.